ABSTRACT
Urethral tumors are rare and aggressive. They usually affect men (2:1) and occur more commonly in white (85% of cases). Soft tissue sarcomas are a heterogeneous group of tumors that arise from embryonic mesoderm. It represents 1% of all cases of urinary tract malignancies and rarely primary affect the ureter. We report a case of male urethral sarcoma. To date, only two similar cases have been published in literature.
Os tumores de uretra são muito raros e bastante agressivos. Acometem mais frequentemente homens (2:1) e são mais comuns na raça branca (85% dos casos). Os sarcomas de tecidos moles são um grupo heterogêneo de tumores que surgem a partir da mesoderme embrionária e representam 1% de todos os casos de doença maligna urinária, raramente acometendo a uretra primariamente. Relamos aqui um caso extremamente raro de sarcoma uretral masculino com somente dois semelhantes publicados na literatura.
Subject(s)
Humans , Male , Aged , Sarcoma/pathology , Urethral Neoplasms/pathology , Rare Diseases/pathology , Fatal OutcomeABSTRACT
Los tumores de uretra, benignos y malignos, en adultos de ambos sexos, son una entidad poco frecuente. La sintomatología, el exámen físico y los estudios complementarios nos permitirán realizar una orientación diagnóstica inicial, pero será la biopsia la que nos dé el diagnóstico definitivo que nos permitirá diferenciar entre un tumor benigno y el cáncer de uretra, cuyo concepto es primordial para la decisión terapéutica ulterior. En general, los tumores uretrales suelen tener una sintomatología común. Los benignos son candidatos para resección quirúrgica, siendo importante considerar aquellas entidades cuyo comportamiento es potencialmente neoplásico ya que deberán tener un seguimiento más estrecho. En cuanto al cáncer uretral hay que considerar que el pronóstico está determinado fundamentalmente por la ubicación anatómica, el tamaño y la profundidad invasora de la neoplasia siendo la histología de menor importancia en la respuesta terapéutica y en la sobrevida. El primer paso terapéutico es el control locorregional quirúrgico de la enfermedad con un margen libre de tumor de 2 cm, debiendo plantearse tratamiento adyuvante con quimioterapia y / o radioterapia en aquellos casos en los que no se pueda conseguir este margen. En casos seleccionados la radioterapia puede ser indicada en monoterapia con intención curativa.
Benign and malignant urethral tumors, in adults of both sexes, are a rare entity. Their symptoms, physical examination, and additional studies will allow us to perform an initial diagnostic approach, but it is the biopsy what will differentiate a benign tumor form cancer. In general, urethral tumors often have common symptoms. Benign tumors can usually be managed with surgical resection, but it is important to consider those entities whose behaviour is potentially neoplastic requiring a closer follow up. The prognosis of urethral cancer is determined mainly by the anatomical location, the size and depth of invasion of the tumor. Histology is of second importance in terms of therapeutic response and survival. The first step in treatment is surgical locoregional control of the disease with a tumor-free margin of 2 cm. Adjuvant chemotherapy and / or radiotherapy should be considered in those cases where this margin cannot be obtained. In selected cases, radiation therapy may be given as monotheraphy with curative intent.
Subject(s)
Humans , Male , Female , Adult , Urethral Neoplasms/diagnosis , Urethral Neoplasms/pathology , Urethral Neoplasms/therapy , Sex Factors , Urethral Neoplasms/classification , PrognosisABSTRACT
The authors report a case of urethral leiomyoma diagnosed during pregnancy, which was conservatively treated up to the 38th week, when the pregnancy was interrupted. Thirty days after delivery, exeresis of the lesion was performed from the upper border of the urethral meatus and sutured with interrupted delayed-absorbable suture. The patient evolved favorably and presented no lesion recurrence during three months of follow up.
Subject(s)
Female , Humans , Pregnancy , Young Adult , Leiomyoma , Pregnancy Complications, Neoplastic , Urethral Neoplasms , Leiomyoma/parasitology , Leiomyoma/surgery , Pregnancy Complications, Neoplastic/pathology , Pregnancy Complications, Neoplastic/surgery , Urethral Neoplasms/pathology , Urethral Neoplasms/surgeryABSTRACT
We present a rare case of clear cell adenocarcinoma of the male bulbomembranous urethra. Mostly these tumors have been described in the female urethral tract with its possible origin from mullerian remnants, wolffian remnants or paraurethral glands. Histologically, these tumors have typically tubulocystic pattern comprising of hobnailed cells with clear glycogenated cytoplasm along with well-defined cytoplasmic membranes. This case is being presented due to its rarity, aggressive behavior and to discuss, trauma as its possible etiological factor
Subject(s)
Adenocarcinoma, Clear Cell/diagnosis , Adenocarcinoma, Clear Cell/pathology , Adenocarcinoma, Clear Cell/surgery , Histocytochemistry , Humans , Magnetic Resonance Imaging , Male , Microscopy , Middle Aged , Penis/pathology , Penis/diagnostic imaging , Urethral Neoplasms/diagnosis , Urethral Neoplasms/pathology , Urethral Neoplasms/surgerySubject(s)
Adenocarcinoma/pathology , Female , Humans , Mesonephroma/pathology , Middle Aged , Urethra/pathology , Urethral Neoplasms/pathologyABSTRACT
El cáncer de uretra es muy infrecuente siendo además la única neoplasia urológica con predilección por las mujeres, por lo que rara vez nos vemos enfrentados a un caso. Son en general de un mal pronóstico y existe escasa literatura al respecto por lo que su manejo es siempre un desafío. Presentamos un caso de carcinoma uretral de una paciente de edad media que lleva 5 años de seguimiento sin recaída.
The cancer of urethra is very infrequent being in addition the only(unique) neoplasia urológica with predilection for them mujeres, for what rarely we meet faced a case. They are in general of an evil forecast (prediction) and scanty literature exists in the matter for what his (her,your) managing is always a challenge. Let's sense before hand a case of carcinoma uretral of a patient of middle ages who goes 5 years of follow-up without relapse.
Subject(s)
Humans , Female , Middle Aged , Adenocarcinoma/surgery , Adenocarcinoma/pathology , Urethral Neoplasms/surgery , Urethral Neoplasms/pathology , Urethral Neoplasms/classificationABSTRACT
Se presentan dos casos de pacientes portadoras de cáncer de uretra, ambos carcinomas de células transicionales, en diferente etapa de propagación tumoral, presentación clínica, tratamiento y resultado final. Se comenta incidencia, principales tipos histológicos y diferentes vías de tratamiento de acuerdo a la literatura médica
Subject(s)
Humans , Female , Middle Aged , Carcinoma, Transitional Cell/surgery , Urethral Neoplasms/surgery , Biopsy , Carcinoma, Transitional Cell/diagnosis , Carcinoma, Transitional Cell/pathology , Neoplasm Metastasis/diagnosis , Urogenital Surgical Procedures/methods , Urethral Neoplasms/diagnosis , Urethral Neoplasms/pathologyABSTRACT
Urethral caruncles are the most common benign tumors in the female urethra, and are usually found in the posterior lip of the urethral meatus of post-menopausal women. It is very rare in young girls. Its etiology is unknown. We add a case of urethral caruncle occurring in a 2 year and 5 month-old girl's mid-urethra. We believe that further accumulation of unusual cases may be helpful in discovering the pathogenesis.
Subject(s)
Child, Preschool , Female , Humans , Urethral Neoplasms/pathologyABSTRACT
Se presenta un caso de adenocarcinoma mesonefroide de la uretra en un paciente de 63 años, tratada con exanteración pelviana anterior logrando una sobrevida de tres años. Se destaca la rareza de este tumor y se revisa la literatura
Subject(s)
Humans , Middle Aged , Adenocarcinoma/pathology , Urethral Neoplasms/pathology , Urethral Neoplasms/therapyABSTRACT
Os autores relatam um caso raro de adenocarcinoma de uretra feminina e tecem comentários baseados na revisäo da literatura